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Home - Products - Chromatin/Epigenetic - Bromodomain - GW 841819X

GW 841819X

CAS No. 146135-18-4

GW 841819X ( GW841819X )

Catalog No. M11985 CAS No. 146135-18-4

GW 841819X is an analogue of (+)-JQ1 and a novel inhibitor of BET bromodomain.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    GW 841819X
  • Note
    Research use only, not for human use.
  • Brief Description
    GW 841819X is an analogue of (+)-JQ1 and a novel inhibitor of BET bromodomain.
  • Description
    GW 841819X is an analogue of (+)-JQ1 and a novel inhibitor of BET bromodomain that displays activity in vivo against NUT-midline carcinoma, multiple myeloma, mixed-lineage leukemia, and acute myeloid leukemia.
  • Synonyms
    GW841819X
  • Pathway
    Chromatin/Epigenetic
  • Target
    Bromodomain
  • Recptor
    Bromodomain
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    146135-18-4
  • Formula Weight
    487.94
  • Molecular Formula
    C26H22ClN5O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(OCC1=CC=CC=C1)N[C@H]2C3=NN=C(C)N3C4=CC=C(OC)C=C4C(C5=CC=C(Cl)C=C5)=N2
  • Chemical Name
    (R)-benzyl (6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepin-4-yl)carbamate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Chung CW, et al. J Med Chem. 2011 Jun 9;54(11):3827-38.
2. Baud MG, et al. Science. 2014 Oct 31;346(6209):638-41.
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